It's no bad thing that the 2 strokes slowly will dissapear, as also past-previous-future governments are/will making an effort to get rid of these stinkers. Compared to 12 years ago, there's not many left as of today; you can see the few remaining clearly by the smoke cloud trailing behind them......
I was out in the middle of nowhere in Rayong province on a CRM250 and was running on fumes when I found a garage that only had gasohol. I filled her up and she ran fine. Dunno about long term effects mind.